When the Duke of Milan is brutally murdered, the Assassin Giovanni Auditore is dispatched to investigate. What he uncovers implicates Italy's most powerful families reaching all the way back to the Vatican itself. As Giovanni draws closer to the truth, he becomes hunted himself. He must expose the conspirators before he joins their ever-growing list of victims.
Giovanni Auditore
Rodrigo Borgia
Federico Auditore
Ezio Auditore
Lorenzo Medici
Uberto Alberti
Pope Sixtus IV
Galleazzo Maria Sforza
Silvio Barbarigo
Shawn Baichoo
Maria Auditore
Claudia Auditore
Lampugnari
Monk/Servant
Ezio's Girlfriend
Prisoner